PM.20.004 – A virtual coach for night shift workers
Route: Personalised medicine: the individual at the centre
cluster question: 073 What effect is the rising 24-hour economy having on human health and performance and how can our knowledge of biorhythms enhance the relationship between the individual and society?
About a fifth of the Dutch work force is engaged in shift work. Reduced fitness while working the night shift […]
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PM.20.005 – NANOSPRESSO-NL
Route: Personalised medicine: the individual at the centre
cluster question: 098 How can we use breakthroughs in basic biomedical research to develop new medicines?
Nucleic acid therapeutics are revolutionizing medicine. However, manufacture, scale-up, distribution and stability are the new limiting factors. NANOSPRESSO-NL aims to […]
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PM.20.006 – Building Muscle Strength
Route: Personalised medicine: the individual at the centre
cluster question: 101 Can we model the human body and use smart technologies for health, nutritional, and toxicity research, drastically reducing the use of laboratory animals at the same time?
Cardiac and skeletal muscle diseases are frequently caused by a genetic defect, which is present at birth and affects entire […]
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PM.20.007 – A modular technology-driven platform to make progress in rare cancer diagnostics and outcomes
Route: Personalised medicine: the individual at the centre
cluster question: 105 How can Big Data and technological innovation (e-health) contribute to health care?
Our overall aim is to create a nationwide data platform to enable frontier science and technology development in the field […]
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PM.20.008 – Netherlands Sudden Cardiac Arrest Network (NET-SCAN)
Route: Personalised medicine: the individual at the centre
cluster question: 088 How can we predict, prevent, and treat cardiovascular diseases (atherosclerosis, heart failure, heart arrhythmia, and thrombosis) in individuals at an early stage?
Sudden Cardiac Arrest (SCA) causes 20% of mortality in the Netherlands and mostly occurs out-of-hospital. The NET-SCAN consortium aims to […]
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PM.20.001 – Exploiting molecular and clinical heterogeneity to personalize sepsis care
Route: Personalised medicine: the individual at the centre
cluster question: 096 How can we improve diagnostics, treatment, and vaccines for immunodeficiencies and infectious diseases?
Sepsis is a life-threatening syndrome caused by a dysregulated response to infection that leads to organ dysfunction. The global burden […]
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PM.20.002 – Anorexia nervosa: the need for personalized treatment
Route: Personalised medicine: the individual at the centre
cluster question: 095 How can we personalise health care, for example by using biomarkers?
Anorexia nervosa (AN) is a severe mental disorder of unknown origin, most common in girls and young women. 2-4% of […]
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PM.20.003 – Biomarkers for personalizing treatment of depression
Route: Personalised medicine: the individual at the centre
cluster question: 095 How can we personalise health care, for example by using biomarkers?
Depression is one of the leading causes of disability. Treatment of depression is based on stepped care, in which different […]
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HCR.20.038 – ASO treatment for Neurodevelopmental Disorders
Route: Personalised medicine: the individual at the centre
cluster question: 083 How do neurological, psychiatric, and mental disorders arise, and how can we prevent, mitigate, or cure them?
Approximately 1% of children are born with severe neurodevelopmental disorders (NDDs) for which there is currently no disease-modifying therapy. However, […]
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