PM.20.022 – Towards better prevention of breast and colorectal cancer
Route: Personalised medicine: the individual at the centre
cluster question: 081 How will our knowledge of genetics play a role in analysing, screening for, and treating diseases?
In the year 2000, the completion of the human genome sequence was heralded as ‘the end of the beginning’, implying […]
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HCR.20.073 – From latent metabolic dysregulation in neurodevelopmental disorders to stress tolerance and resilience in health and disease – BALANCE
Route: Health care research, sickness prevention and treatment
cluster question: 077 What do non-genetic factors contribute to personal traits and disease processes?
Mendelian NeuroDevelopmental Disorders (NDDs) represent a major unsolved medical and socio-economic problem. The only so far treatable NDDs are inborn […]
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HCR.20.052 – Towards an artificial womb for extremely premature born infants
Route: Health care research, sickness prevention and treatment
cluster question: 091 Pregnancy, childbirth, and menopause - can we make them better for women?
After birth, each infant faces a physiologic transition from maternal-placental life-support to (self-supportive) extra-uterine life. For prematurely born infants, this […]
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HCR.20.064 – MICROSTART: establishing a healthy gut microbiome in preterm newborns in the western world
Route: Health care research, sickness prevention and treatment
cluster question: 086 Intestinal disorders, and specifically the relationship between gut flora and health: what can we do to benefit our gut flora?
Research question: What is the relation between the gut microbiome and early life health and disease status in preterm infants, […]
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HCR.20.041 – Sargassum Seaweeds: potential for fighting dementia
Route: Health care research, sickness prevention and treatment
cluster question: 082 How does the central nervous system develop and how can we counteract degeneration processes in that system?
Alzheimer’s disease, the most common form of dementia, is characterized by a progressive cognitive and consequently functional decline, leading to […]
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BD.20.004 – TARES: Technology Assisted Review and Evidence Synthesis
Route: Creating Value through responsible access to and use of big data
cluster question: 112 Can we use Big Data and Big Data collection to define values, generate insights, and get answers?
Any decision making in health or preventive care, in any medical domain, is best served with a rapid, comprehensive and […]
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RGM.20.009 – REStoration Of LUng funcTIon lOss iN emphysema (RESOLUTION)
Route: Regenerative medicine: game changer moving to broad areas of application
cluster question: 089 How can we improve our understanding and treatment of pulmonary diseases?
Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death worldwide. The prevalence of CODP will increase […]
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PM.20.044 – Personalized focused MR-guided thermo-chemotherapy for breast conserving surgery (PERFECT-4-BCS)
Route: Personalised medicine: the individual at the centre
cluster question: 104 How do we develop minimally invasive techniques and interventions for diagnosis, prognosis, and treatment?
Neoadjuvant chemotherapy (NAC) is the standard procedure to shrink breast cancers to make them operable or eligible for breast conserving […]
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PM.20.026 – Integration of innovative biomedical technologies for optimized personalized treatments for epilepsy
Route: Personalised medicine: the individual at the centre
cluster question: 098 How can we use breakthroughs in basic biomedical research to develop new medicines?
Approximately 70 million people worldwide (180,000 in the Netherlands) are affected by a type of epilepsy. Epileptic syndromes show a […]
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PM.20.032 – Improving diagnostics and prognostics in disorders of consciousness: An integrative approach
Route: Personalised medicine: the individual at the centre
cluster question: 104 How do we develop minimally invasive techniques and interventions for diagnosis, prognosis, and treatment?
Due to improvements in emergency treatment and life support, more people survive life-threatening incidents such as a cardiac arrest and […]
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