PM.20.011 – NutriDutcH Personalised Nutrition in Dutch Hospitals for quicker and long-term recovery

Route: Personalised medicine: the individual at the centre

Cluster question: 095 How can we personalise health care, for example by using biomarkers?

How can we personalize healthcare, for example by using biomarkers?’ is one of the cluster questions that are posed in the Dutch Science Agenda (NWA). An important question for nutrition, as we know from clinical practice that optimal nutrition is critical for shortening hospitalization duration and for reducing complications and costs. In fact, optimal nutrition could save Dutch hospitals 1.1 to 1.5 billion Euro annually.

Nutrition plays an essential role in health, especially during and after disease or surgery. It is evident that nutrition delivers energy and building blocks. However, the influence of nutrition on individual health during disease is extremely complex. Why do people lose appetite when they are ill? What is the influence of personal dietary habits on hospitalization and recovery? Which food is optimal for which people at what moment? What is the influence of the circadian rhythm? How can we influence nutritional motivation of individual patients? This knowledge is important to provide personalized nutritional advice for improving recovery after hospitalization.
Our proposal addresses the intricate links between the intestine, the muscles, and the brain as a biological basis for personalised nutrition from the hospital to home.

Here, we aim to address the following general research questions: Which gut signals (e.g. disease related inflammatory processes, microbiome, appetite-regulating peptide hormones etc) influence eating behaviour, motivation and muscle mass as a result? Which interventions can improve appetite, eating behaviour, and muscle mass? How does this relate to a healthy situation? What biological correlates predict the empowerment of people at risk to make the required changes effectively? How can we translate individual biological parameters to personalised lifestyle and nutritional advice to support the behavioural change necessary for a better and quicker recovery after hospitalization? How can we reduce costs?

Keywords

brain, Gut, in-hospital, muscle, nutrition

Other organisations

Donders Institute for Brain, Eindhoven University of Technology (TU/e), Maastricht University Medical Center (MUMC), Radboud Medical Center (RUMC), Radboud Universiteit Nijmegen (RU), TNO, UMC Utrecht (UMCU), Universitair Medisch Centrum Groningen (UMCG), Universiteit Twente (UT), University of Amsterdam (UvA), University of Applied Sciences Amsterdam, University of Applied Sciences Arnhem Nijmegen, Vrije Universiteit Amsterdam (VU), Wageningen Universities and Research (WUR)

Submitter

Organisation Amsterdam University Medical Centers (Amsterdam UMC)
Name Dr. M.R. (Maarten) Soeters, MD
E-mail m.r.soeters@amsterdamumc.nl
Website http://www.nutridutchresearch.com/