PM.20.002 – Anorexia nervosa: the need for personalized treatment

Route: Personalised medicine: the individual at the centre

Cluster question: 095 How can we personalise health care, for example by using biomarkers?

Anorexia nervosa (AN) is a severe mental disorder of unknown origin, most common in girls and young women. 2-4% of women develop AN in their lifetime and about 5% dies from this disease, making it the most lethal of all psychiatric disorders. Treatment is only successful in about half of the patients and many patients suffer additionally from anxiety, depression, trauma and other disorders.
The goal of this research is to determine why people so often experience their treatment not helpful and to develop better etiology-based treatments.
This is achieved by examining AN-patients about their current treatment success/failure and experimenting with neurobiology-based innovative personalized therapies. Data collection comprises new ways of measuring stress levels, biological data and qualitative (lived experience-based) research. Finally, all the collected data and algorithms are made available as open data for future research. The research is conducted by a unique team of multidisciplinary scientists and practitioners.


Anorexia nervosa, neurobiology, supported treatment decision

Other organisations

Amarum (GG-Net), Donders Institute for Brain, Philips, Rintveld (Altrecht), UMCU, WEET


Organisation Utrecht University (UU)
Name Prof.dr. A. (Annemarie) van Elburg