HCR.20.092 – A transdiagnostic approach to fatigue in chronic disease

Route: Health care research, sickness prevention and treatment

Cluster question: 076 What are the consequences of chronic disorders, stress, and disabilities and what is the best way to deal with them?

Fatigue is highly prevalent and burdensome symptom in chronic disease. Treatment options are limited and little is known about the (neuro)biological and behavioural determinants of fatigue. There is increasing evidence suggesting that fatigue is a generic symptom in chronic disease and associated with transdiagnostic factors. The primary aim of the consortium is: 1) to increase our knowledge about the transdiagnostic determinants of chronic fatigue in chronic disease; 2) to develop and test the efficacy of transdiagnostic interventions for fatigue in chronic disease.


chronic disease, Fatigue, interventions, neurobiology, Personalised Medicine, transdiagnostic


Organisation Amsterdam UMC (AMC)
Name Prof. dr. J.A. (Hans) Knoop
E-mail hans.knoop@amsterdamumc.nl
Website https://www.amc.nl/web/research-75/person-1/prof.-j.a.-knoop-phd.htm