HCR.20.085 – Nanoplastics in the brain
One of the biggest current threats that humanity faces is the climate change and environmental alterations that can have tremendous impact on human health and well-being. Recent evidence indicates that environmental pollutants can affect the function of several organs, including lung, heart and the brain resulting in pulmonary, cardiovascular and metabolic diseases. There is a rising awareness of the presence of micro and nano-sized plastics in our environment and the consequent impact on (human) health. Nano-sized objects have been found in the brain, raising the question of their potential detrimental effects on brain function. Here we aim to investigate the ability of micro and nano-plastics to infiltrate the brain in advanced in vitro models, allowing us faithfully measure the internalisation, intracellular distribution and ultimate effects on the human brain.
immune cells, Nanoplastics, stem cells
|Organisation||University of Groningen (RUG)|
|Name||Prof. dr. A.M. (Amalia) Dolga|